(Z-IETD)2-Rh 110 (trifluoroacetate salt)

(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8.1 Upon enzymatic cleavage by caspase-8, rhodamine 110 (Item No. 19061) is released and its fluorescence can be used to quantify caspase-8 activity. Rhodamine 110 displays excitation/emission maxima of 496/520 nm, respectively.WARNING This product is not for human or veterinary use.

[1] HEIDI K BAUMGARTNER. Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins.[J]. American journal of physiology. Gastrointestinal and liver physiology, 2007, 293 1: G296-307. DOI: 10.1152/ajpgi.00103.2007