CT1812 (0.3-3 mg/kg, i.v., once time) selectively reduces Aβ oligomer extracellular concentrations in transgenic hAPP/PS1 mice[1].
CT1812 (10 mg/kg, p.o., daily, 9-10 weeks) improves cognitive performance in transgenic Thy1 huAPPSwe/Lnd+ male mice[1].