Cloconazole is an antifungal azole drug.
ChEBI: Croconazole is an imidazole antifungal drug, a conazole antifungal drug, a member of monochlorobenzenes and an aromatic ether.
Topical treatment of mycoses of the skin induced or sustained by fungi such as dermatophytes and yeasts.
Broad-spectrum imidazole antimycotic with activity against almost all pathogenic fungi.
Local irritations and allergic reactions after topical treatment may occur in rare cases and are mainly due to the galenic formulation.
When male rabbits are administered croconazole by
intravenous injection, as many as 16 metabolites are
excreted in the urine and 13 metabolites are identified.
The biotransformation reaction of croconazole includes
ring hydroxylation, O-dechlorobenzylation, and the loss
of the imidazole ring.
