SIA Crosslinker is a non-cleavable, water-soluble crosslinker containig an NHS ester and an iodine group. The NHS ester is reactive toward amines while the iodine reacts with thiol groups.
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms
forms water soluble carboxylate derivatives
A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent.
Spacer Arm: 1.5 Angstroms
SIA Crosslinker is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.