恩格林A
恩格林A 性质
| 沸点 | 550.3±50.0 °C(Predicted) |
|---|---|
| 密度 | 1.20±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 形态 | 固体 |
| 酸度系数(pKa) | 12.88±0.10(Predicted) |
| 颜色 | 白色至浅黄色 |
恩格林A 用途与合成方法
|
hTRPC4 11.2 nM (EC 50 ) |
hTRPC5 7.6 nM (EC 50 ) |
Englerin A (0.15-2500 nM; 48 h) characteristic concentration-dependent suppresses cells growth of the A-498 cells treated with the control siRNA while has little effect on the growth of cells treated with TRPC4 siRNAs.
Englerin A (0.001nM-10 μM; 48 h) inhibits cells viability in HEK293T cells overexpressing TRPC5.
Englerin A (3 nM; 1-240 s) evokes sustained elevation of the intracellular Ca
2+
concentration within 1 min in HEK 293 cells over-expressing human TRPC4.
Englerin A (0.1-1000 nM; 1-300 s) evokes intracellular Ca
2+
elevations in A498 cells as well with an EC
50
of 10 nM.
Englerin A (5 mg/kg; i.p daily except Sunday) markedly inhibits tumor growth during the 2-week treatment period in mice.
恩格林A 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-133168 | 1 mg | 3950 | ||
| 2024-08-19 | HY-133168 | 恩格林A | 1094250-15-3 | 5 mg | 9980 |
