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2,5-Dimethylindole

Basic information Description Sources Safety Related Supplier
2,5-Dimethylindole Basic information
2,5-Dimethylindole Chemical Properties
  • Melting point:112-113 °C(lit.)
  • Boiling point:254.33°C (rough estimate)
  • Density 1.0353 (rough estimate)
  • refractive index 1.5000 (estimate)
  • form Solid
  • pka17.75±0.30(Predicted)
  • color Off-white to pale pink or light brown
  • CAS DataBase Reference1196-79-8(CAS DataBase Reference)
  • NIST Chemistry Reference1H-indole, 2,5-dimethyl-(1196-79-8)
Safety Information
  • Hazard Codes Xi
  • Risk Statements 37/38-41
  • Safety Statements 26-39
  • WGK Germany 3
  • Hazard Note Irritant
  • HS Code 29339900
MSDS
2,5-Dimethylindole Usage And Synthesis
  • Description2, 5-Dimethylindole is a kind of carbazole-system derived indole compound, which is valuable in the manufacturing of perfume. It is also a useful chemical intermediate. It is usually used as reactant in the following reaction: stereoselective synthesis of indolines via palladium-catalyzed asymmetric hydrogenation of unprotected indoles; stereoselective preparation of substituted indoles via rhodium-catalyzed enantioselective coupling reaction of indoles with diazo compounds; enantioselective synthesis of fluorene derivatives via Friedel-Crafts reactions; preparation of bis-indolyldihydroxybenzoquinones by addition indoles to dichlorobenzoquinone promoted by Bronsted acid; Reaction with hydroxypyrazolines.
  • Sourceshttps://www.sigmaaldrich.com/catalog/product/aldrich/d166006?lang=en&region=US
    https://books.google.com/books?isbn=0470188073
  • Chemical PropertiesOff-white to pale pink or light brown solid
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