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Tenofovir Alafenamide

Basic information Description Safety Related Supplier
Tenofovir Alafenamide Basic information
Tenofovir Alafenamide Chemical Properties
  • Boiling point:640.4±65.0 °C(Predicted)
  • Density 1.39±0.1 g/cm3(Predicted)
  • pka4.21±0.10(Predicted)
Tenofovir Alafenamide Usage And Synthesis
  • DescriptionTenofovir Alafenamide (GS-7340) is a prodrug of tenofovir, which is a reverse transcriptase inhibitor, used to treat HIV and Hepatitis B.-Reverse Transcriptase inhibitor. It was developed by Gilead Sciences. Compared to tenofovir disoproxil fumarate, tenofovir alafenamide has a greater antiviral activity and better distribution into lymphoid tissues.
  • DefinitionChEBI: An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)( henoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection.
Tenofovir Alafenamide(379270-37-8)Related Product Information
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