TGFβRI-IN-2

Chemical Properties

Boiling point	664.2±65.0 °C(Predicted)
Density	1.450±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: 2mg/mL, clear
form	Solid
pka	15.82±0.40(Predicted)
color	White to off-white
InChI	1S/C20H15ClFN5O2/c1-11-8-25-15(13-6-12(21)2-3-14(13)22)7-17(11)27-16-4-5-24-9-18(16)26(20(27)29)10-19(23)28/h2-9H,10H2,1H3,(H2,23,28)
InChIKey	LVEUPFUJRKZPEN-UHFFFAOYSA-N
SMILES	Fc1c(cc(cc1)Cl)c2ncc(c(c2)[n]3c4c([n]([c]3=O)CC(=O)N)cncc4)C

WGK Germany	WGK 3
Storage Class	11 - Combustible Solids

Animal Model:	Rats^[1]
Dosage:	50, 150 and 500 mg/kg
Administration:	Oral administation; 50, 150 and 500 mg/kg; 5 days
Result:	Induced cardiovalvulopathy in both the medium and high dose animal groups.