1-Oleoyl-sn-glycero-3-phosphocholine

Product Name1-Oleoyl-sn-glycero-3-phosphocholine
CAS19420-56-5
MFC26H52NO7P
MW521.67
EINECS
MOL File19420-56-5.mol

Chemical Properties

storage temp.	-20°C
solubility	PBS (pH 7.2): 2 mg/ml
form	powder
color	White to off-white
biological source	synthetic
BRN	4033747
InChIKey	YAMUFBLWGFFICM-PTGWMXDISA-N
SMILES	O[C@](COP([O-])(OCC[N+](C)(C)C)=O)([H])COC(CCCCCCC/C=C\CCCCCCCC)=O

Safety Information

Safety Statements	22-24/25
WGK Germany	3
F	10
Storage Class	11 - Combustible Solids

MSDS

Provider	Language
SigmaAldrich	English

Usage And Synthesis

Uses

1-Oleoyl-sn-glycero-3-phosphocholine may be used as a reference for the analysis of lysolecithins extracted from tissues and cell membranes.

Uses

1-Oleoyl-sn-glycero-3-phosphocholine is a marker contained in biological sample for determination of obesity and screening method.

Uses

18:1 Lyso PC is suitable for use as a lysophospholipidmediator to compare the effect of sphingosylphosphorylcholine (SPC). It has been used as a supplement in Yeast nitrogen base (YNB) medium to rescue choline auxotrophy.

Definition

ChEBI: 1-O-oleoyl-sn-glycero-3-phosphocholine is an oleoyl-sn-glycero-3-phosphocholine in which the acyl group at position 1 is (9Z)-octadecenoyl (oleoyl) and the hydroxy group at position 2 is unsubstituted. It is a lysophosphatidylcholine (18:1/0:0), a 1-O-acyl-sn-glycero-3-phosphocholine and an oleoyl-sn-glycero-3-phosphocholine.

General Description

18:1 Lyso PC (1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine) is an endogenous lipid. It has one hydrocarbon tail.

Biochem/physiol Actions

Lysophosphatidylcholine (LPC) participates as a key factor in the atherogenic activity of oxidized low-density lipoprotein (Ox-LDL). It is a well-known cluster of differentiation 1(CD1) ligand.