Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) protects against sepsis-induced lethality on albino ICR mice[4].
Lysophosphatidylcholines (0.1-20 mg/kg, Oral, single dose) enhances bacterial clearance, blocks cecal ligation and puncture (CLP)-induced neutrophil deactivation and increases bactericidal activity of neutrophils[4].
| Animal Model: | Albino ICR mice [4] |
| Dosage: | 0.1 mg/kg, 1 mg/kg, 10 mg/kg, 20 mg/kg |
| Administration: | Oral |
| Result: | Provided significant protection against cecal ligation and puncture (CLP)-induced lethality at a dose of 1 mg/kg. |
