兔多克隆抗体TO EGFR

兔多克隆抗体to EGFR

Rabbit

适用于: IP, WB, IHC-P

与反应: Mouse, Human
预测可用于: Monkey

Synthetic peptide within Human EGFR aa 1150-1210. The exact sequence is proprietary.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EGFR antibody (ab245363)

Formalin-fixed, paraffin-embedded human placenta tissue stained for EGFR with ab245363 at a 1/1,000 dilution in immunohistochemical analysis. DAB staining.

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Anti-EGFR Polyclonal Antibody是以Anti-EGFR为抗原制得的多克隆免疫抗体，可以特异性结合EGFR，主要用于检测EGFR的Western Blot、IHC-P、IF、ELISA、Co-IP等多种免疫学实验。