FAUC 213 (7.5-30 mg/kg; orally; single dose) significantly reduces this elevation in AMPH-induced locomotor hyper-activity only pre-treatment with 30 mg/kg. FAUC 213 significantly restores the prepulse inhibition (PPI) reduction caused by the apomorphine (APO) treatment with 30 mg/kg[1].
| Animal Model: | Male adult Wistar rats weighing 300-350 g[1] |
| Dosage: | 7.5, 15, 30 mg/kg |
| Administration: | Orally; single dose |
| Result: | Significantly reduced this elevation in amphetamin (AMPH)-induced locomotor hyper-activity only pre-treatment with 30 mg/kg.
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