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4-Chloro-4'-hydroxybenzophenone

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4-Chloro-4'-hydroxybenzophenone Basic information
4-Chloro-4'-hydroxybenzophenone Chemical Properties
Safety Information
MSDS
4-Chloro-4'-hydroxybenzophenone Usage And Synthesis
  • Chemical Propertieslight grey to beige-brown powder
  • UsesThe Impurity of Fenofibric acid (42017-89-0), the active metabolite of fenofibrate which increases Apolipoprotein A-I–Mediated High-Density Lipoprotein Biogenesis by enhancing transcription of ATP-Binding cassette transporter A1 gene in a liver X receptor
  • PreparationPreparation by Fries rearrangement of phenyl p-chloro-benzoate,
    ? in the presence of aluminium chloride, without solvent, at 160° for 5 min, between 120° and 160° (good yield) or at 130° for 1 h, then at 160° for 1 h (10%) or in refluxing chlorobenzene for 10 h (52%);
    ? in the presence of trifluoromethanesulfonic acid at 45–55° (94%).
4-Chloro-4'-hydroxybenzophenone Preparation Products And Raw materials
4-Chloro-4'-hydroxybenzophenone(42019-78-3)Related Product Information
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