生长抑素肽类似物
生长抑素肽类似物 性质
| 沸点 | 1732.9±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.235±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 酸度系数(pKa) | 2.93±0.70(Predicted) |
| 形态 | 粉末 |
| 颜色 | 白色至米白色 |
| 水溶解性 | Soluble to 0.30 mg/ml in water |
生长抑素肽类似物 用途与合成方法
IC50: 30.9 nM; Ki: 52 nM (somatostatin receptor 1)IC50: 345 nM (somatostatin receptor 3)
CH275 (100 nM) activates neprilysin activity, wheras treatment with cyclo-SRIF can complete this activation in vitro in primary neuron-based cell culture system, a mixture of wildtype hippocampal, cortical and striatal neuron.
CH275 (osmotic pump administration; 56 μM; two weeks) decreases the level of neprilysin/SRIF in the App knock-in mice.CH275 directly injects into the Lacunosum molecular layer (Lmol) layer of 2-month-old App NL-G-F mice for four months. App NL-G-F mice begin to exhibit Aβ plaques at two months of age, but CH275 leads to robustly increased the expression of neprilysin in hippocampus which is paralleled by a clear reduction in Aβ plaque load in the same region, and without causing any toxic side effects.
生长抑素肽类似物 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-P1206 | 1 mg | 2600 | ||
| 2024-08-19 | HY-P1206 | 5 mg | 8300 |
