10-Hydroxybenzo[h]quinoline

152583-10-3

33155-90-7

10-Bromobenzo[h]quinoline (0.15 mmol, 39 mg) was added to an oven-dried screw-capped vial with carboxylic acid (0.3 mmol), silver carbonate (Ag-based, 0.165 mmol, 22 mg), potassium fluoride (0.15 mmol, 9 mg) and p-xylene (0.5 mL). The reaction mixture was stirred vigorously at 150 °C for 24 hours. After completion of the reaction, the mixture was cooled to room temperature and diluted with ethyl acetate. Subsequently, the solvent was removed by distillation under reduced pressure and the final product was purified by silica gel column chromatography.