PDK1 抑制剂
PDK1 抑制剂 性质
| 沸点 | 724.4±60.0 °C(Predicted) |
|---|---|
| 密度 | 1.398 |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 粉末 |
| 酸度系数(pKa) | 11.48±0.20(Predicted) |
PDK1 抑制剂 用途与合成方法
PDK1
Cell counting of U87MG-derived glioma stem cells (GSCs) confirms that Alisertib and, to a minor extent, MP7 (PDK1 inhibitor) are able to decrease the number of viable cells. When combined together, GSC viability is further reduced with respect to single-treated cells. As observed in U87MG cells, when used at the highest concentrations (i.e., 1.5 μM Alisertib and 2.5 μM MP7), a significant enhancement in the number of dead cells is evidenced. Following 72 h treatment, MP7 alone does not show a significant inhibition of glioblastoma multiforme (GBM) proliferation. MP7 has been shown to have only minimal effects on monolayer cell growth in several cancer cell lines, with IC 50 values in the micromolar range.
PDK1 抑制剂 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-04-30 | HY-14440 | PDK1 抑制剂 | 1001409-50-2 | 5mg | 1300 |
| 2024-04-30 | HY-14440 | PDK1 抑制剂 | 1001409-50-2 | 10mg | 2100 |
