THAXTOMINE A

Thaxtomin A is a major phytotoxin produced by S. scabies, gram-positive soil bacterium responsible for producing scabs on tubers and root vegetables. This bacterial metabolite acts as a virulence factor in the common scab potato disease and demonstrates herbicidal activity against the dicotyledon weeds B. campestris and A. retroflexus.

Thaxtomin A is a phytotoxin produced by Streptomyces scabies and other Streptomyces species, the causative agents of common scab disease in potato and other taproot crops.

[1] SYLVAIN LERAT. Involvement of the plant polymer Suberin and the disaccharide cellobiose in triggering thaxtomin A biosynthesis, a phytotoxin produced by the pathogenic agent streptomyces scabies.[J]. Phytopathology, 2010, 100 1: 91-96. DOI: 10.1094/phyto-100-1-0091
[2] HONGBO ZHANG. Total Synthesis of Thaxtomin A and Its Stereoisomers and Findings of Their Biological Activities[J]. Organic Letters, 2013, 15 22: 5670-5673. DOI: 10.1021/ol4026556