tentoxin, a highly
effective phytotoxin from Alternaria alternata f. sp. tenuis,
is too expensive to be used as a commercial herbicide (80).
Efforts to discover a cheaper, synthetic analogue of tentoxin
with similar herbicidal properties have failed.
Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important crops.
Tentoxin, is a natural cyclic tetrapeptide, isolated from Alternaria alternata, which induces chlorosis in plants, and thus can be used as a potential natural herbicide.
ChEBI: Tentoxin is a lactam.
[1] STEPHEN O DUKE. Natural toxins for use in pest management.[J]. Toxins, 2010, 2 8: 1943-1962. DOI:
10.3390/toxins2081943[2] STEPHEN O DUKE F E D. Modes of action of microbially-produced phytotoxins.[J]. ACS Applied Electronic Materials, 2011: 1038-1064. DOI:
10.3390/toxins3081038