Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA), important targets in oncology.
IC 50
Human PKCα: 4-9 nM (); PKC-βI: 4-9 nM (); PKC-βII: 4-9 nM (); Human PKCγ: 4-9 nM (); Human PKCδ: 4-9 nM (); Human PKCε: 4-9 nM (); human PKCη: 150 nM (); PKA
