Adenosine 5′-(trihydrogen diphosphate), 2-chloro-, trisodium salt

2-Chloro-ADP (2-Chloroadenosine 5′-diphosphate) sodium is a Adenosine 5'-diphosphate (ADP; HY-W010918) derivative that induces human platelet aggregation and inhibits stimulated adenylate cyclase[1]. 2-Chloro-ADP sodium inhibits mortalin nucleotide-binding domain (NBD) with a Ki of 45.05 μM[2].

[1] N J Cusack, et al. Competitive inhibition by adenosine 5'-triphosphate of the actions on human platelets of 2-chloroadenosine 5'-diphosphate, 2-azidoadenosine 5'-diphosphate and 2-methylthioadenosine 5'-diphosphate. Br J Pharmacol. 1982 Oct;77(2):329-33. DOI:10.1111/j.1476-5381.1982.tb09302.x
[2] Mitchell A Moseng, et al. 2- and N6-functionalized adenosine-5'-diphosphate analogs for the inhibition of mortalin. FEBS Lett. 2019 Aug;593(15):2030-2039. DOI:10.1002/1873-3468.13475
[3] D G SATCHELL  M H M. Inhibitory effects of adenine nucleotide analogs on the isolated guinea-pig taenia coli.[J]. Journal of Pharmacology and Experimental Therapeutics, 1975, 195 3: 540-548.
[4] G GOUGH  Frank M  M Helen Maguire. 2-Chloroadenosine 5’-Phosphate and 2-Chloroadenosine 5’-Diphosphate, Parmacologically Active Nucleotide Analogs[J]. Journal of Medicinal Chemistry, 1969, 12 3: 494-498. DOI: 10.1021/jm00303a604