diphyllin

Product Namediphyllin
CAS22055-22-7
MFC21H16O7
MW380.35
EINECS
MOL File22055-22-7.mol

Chemical Properties

Melting point	290℃ (methanol )
Boiling point	638.8±55.0 °C(Predicted)
Density	1.445±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	2-8°C
solubility	Soluble in DMSO
pka	7.82±0.20(Predicted)
form	powder
color	white to light brown

Usage And Synthesis

Uses

Diphyllin has been used to study its antibacterial and antibiofilm activities against fish pathogens.

Definition

ChEBI: Diphyllin is a lignan.

General Description

Diphyllin, a major glycoside compound, is a plant-derived lignan. It is present in Cleistanthus collinus.

Biochem/physiol Actions

Diphyllin is a natural arylnaphthalene that exhibits potent anticancer and antiviral activities. It is a potent inhibitor of vacuolar H(+)-ATPase (V-ATPase) that inhibits lysosomal acidification in osteoclasts.

Preparation Products And Raw materials

Raw materials

2,3-Naphthalenedicarboxylic acid, 1-(1,3-benzodioxol-5-yl)-4-hydroxy-6,7-dimethoxy-, 2,3-diethyl ester Naphtho[2,3-c]furan-1,4-dione, 9-(1,3-benzodioxol-5-yl)-3,3a,9,9a-tetrahydro-9-hydroxy-6,7-dimethoxy-, [3aS-(3aα,9α,9aα)]- (9CI)9-(benzo[d][1,3]dioxol-5-yl)-6,7-dimethoxy-1-oxo-1,3-dihydronaphtho[2,3-c]furan-4-yl acetate 6-Bromoveratraldehyde Diethyl ether

Preparation Products