倍氯米松
倍氯米松 性质
| 熔点 | 217- 222°C (dec.) |
|---|---|
| 沸点 | 600.2±55.0 °C(Predicted) |
| 密度 | 1.35±0.1 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 二恶烷(少量,超声处理)、DMSO(少量溶解)、乙酸乙酯(少量溶解)、甲烷 |
| 形态 | 固体 |
| 酸度系数(pKa) | 12.17±0.70(Predicted) |
| 颜色 | 白色至浅棕色 |
| Merck | 13,1020 |
| 稳定性 | 吸湿性 |
| InChIKey | NBMKJKDGKREAPL-WOOYFSPWSA-N |
| SMILES | [H][C@]12C[C@@H](C)[C@@](O)(C(=O)CO)[C@]1(C)C[C@@H](O)[C@@]3(Cl)[C@]2([H])CCC4=CC(=O)C=C[C@@]34C |
| CAS 数据库 | 4419-39-0(CAS DataBase Reference) |
倍氯米松 用途与合成方法
Glucocorticoid Receptor
An inhibition of the normal physiological neutrophil migration and of neutrophil chemotaxis directed by wounding-induced inflammation is detected at 4 h after administration of 25 μM Beclomethasone. Tumour cell invasion and micrometastasis is also reduced in embryos incubated in 25 μM Beclomethasone 4 h before implantation. In addition, the lysyl oxidase inhibitor β-aminoproprionitrile (βAPN) largely reduces fibrillar collagen and enhances the CHT-TF transmigration of neutrophils, leading to a significant increase of tumour cell invasion and subsequent formation of micrometastases. Notably, βAPN inhibits neutrophil chemotaxis induced by inflammation, indicating that the increase of tumour cell invasion in βAPN-treated embryos is correlated with enhanced non-pathological neutrophil migration, but not with inflammation.
倍氯米松 化学药品说明书
倍氯米松 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-B1540R | 倍氯米松 | 4419-39-0 | 5 mg | 640 |
| 2026-09-15 | HY-B1540R | 倍氯米松 | 4419-39-0 | 10 mg | 960 |