Mca-EVKMDAEF-K(Dnp)-NH2 is a fluorogenic substrate for β-secretase.1 Upon cleavage by β-secretase, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify β-secretase activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.WARNING This product is not for human or veterinary use.
[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.