1,1,1,3,3,3-HEXAFLUOROISOPROPYL METHACRYLATE

Hexafluoroisopropyl methacrylate (HFA) is a transparent, colorless liquid. It is primarily used in the synthesis of resins and coatings to improve their weather resistance, water resistance, and stain resistance; it is also used as a sheathing material for plastic optical fibers, as well as in contact lenses and computer toners. Furthermore, it can be used as an intermediate in pharmaceuticals and pesticides.

Clear colorless liquid

To a 1L four-necked flask equipped with mechanical stirring, condenser tube (water-cooled), and thermometer was added 1.5 g of p-methoxyphenol, 30% fuming sulfuric acid 60 g, stirring, and then add dropwise at room temperature a mixture of methacrylic acid and hexafluoroisopropanol, to which methacrylic acid 103 g (1.5 g) was added. acid 103 g (1.2 mol), hexafluoroisopropanol 168 g (1 mol); the reaction was exothermic, and the titration time was about 20 min; at the end of the titration, the After the end of the reaction, the reaction was warmed up to 94C for about 3 h. After the end of the reaction, hexafluoroisopropyl methacrylate 217 g was obtained by simple distillation at atmospheric pressure, the yield was about 92%, no need to further refinement. The content of hexafluoroisopropyl methacrylate reached 99.2% without further purification.