2,5-Dimethoxybenzo-1,4-quinone

2,5-DMBQ (2,5-Dimethoxybenzoquinone) serves as an extracellular reductant. 2,5-DMBQ is involved in a crucial redox cycle, namely the extracellular hydroquinone-quinone redox cycle. In this cycle, 2,5-DMBQ is capable of reducing extracellular Fe3 and generating H2O2. 2,5-DMBQ plays a pivotal role in the biodegradation mechanism of brown rot fungal, assisting the fungi in decomposing and utilizing organic matter[1][2].

ChEBI: Thermophillin is a member of benzoquinones and a member of p-quinones.

Journal of the American Chemical Society, 117, p. 8879, 1995 DOI: 10.1021/ja00139a033

[1] Varela E, et al. Effect of pH and oxalate on hydroquinone-derived hydroxyl radical formation during brown rot wood degradation. Appl Environ Microbiol. 2003;69(10):6025-6031. DOI:10.1128/AEM.69.10.6025-6031.2003
[2] Jensen KA Jr, et al. Pathways for extracellular Fenton chemistry in the brown rot basidiomycete Gloeophyllum trabeum. Appl Environ Microbiol. 2001 Jun;67(6):2705-11. DOI:10.1128/AEM.67.6.2705-2711.2001