松茋
松茋 性质
| 熔点 | 117-118℃ |
|---|---|
| 密度 | 1.252 |
| 储存条件 | Keep in dark place,Inert atmosphere,2-8°C |
| 溶解度 | 在DMSO中的溶解度≥13mg/mL |
| 形态 | 粉末 |
| 颜色 | 白色至棕褐色 |
| InChI | InChI=1S/C15H14O3/c1-18-15-9-12(8-14(17)10-15)3-2-11-4-6-13(16)7-5-11/h2-10,16-17H,1H3/b3-2+ |
| InChIKey | KUWZXOMQXYWKBS-NSCUHMNNSA-N |
| SMILES | C1(O)=CC(OC)=CC(/C=C/C2=CC=C(O)C=C2)=C1 |
松茋 用途与合成方法
Pinostilbene (0- 40 μM; 24 hours, 48 hours) does not cause significant inhibition on the growth of normal colon cells.
Pinostilbene (20 μM, 40 μM; 24 hours, 48 hours) causes a significant and dose-dependent increase in the percentage of cells in S phase in both HCT116 and HT29 cells compared to the control cells.
Pinostilbene at μM also induces a modest increase of cell population in G2/M phase in HT29 cells.
Pinostilbene(20 μM, 40 μM; 24 hours, 48 hours) modulates expression of key signaling proteins related to cell proliferation and apoptosis.
Pinostilbene also acts as a resveratrol methylated derivative and displays protective effects against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
Cell Viability Assay
| Cell Line: | HCT116 cells, HT29 cells |
| Concentration: | 24 hours, 48 hours |
| Incubation Time: | 0-100 μM |
| Result: | Inhibited the growth of two human colon cancer cells. |
Apoptosis Analysis
| Cell Line: | HCT116 cells, HT29 cells |
| Concentration: | 20 μM, 40 μM |
| Incubation Time: | 24 hours, 48 hours |
| Result: | Caused a significant and dose-dependent increase in the percentage of cells in S phase. |
Cell Viability Assay
| Cell Line: | HCT116 cells |
| Concentration: | 20 μM,40 μM |
| Incubation Time: | 24 hours, 48 hours |
| Result: | Significantly increased the expression levels of p53, Bax, cleaved caspase-3, cleaved PARP and p21 Cip1/Waf1 , while decreased the expression levels of cyclin E and p-Rb. |
安全信息
| 危险品标志 | Xi,N |
|---|---|
| 危险类别码 | 37/38-41-50 |
| 安全说明 | 26-39-61 |
| 危险品运输编号 | UN 3077 9 / PGIII |
| WGK Germany | 3 |
| 海关编码 | 2909.50.5000 |
| 存储类别 | 11 - 可燃固体 |
| 危险性类别 | 严重眼损伤 类别1 经皮刺激 类别2 特异性靶器官毒性-一次接触，类别3 |
松茋 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-N3059 | 松茋 | 42438-89-1 | 5mg | 480 |
| 2026-09-15 | HY-N3059 | 松茋 | 42438-89-1 | 10 mM * 1 mL in DMSO | 528 |
