ChEBI: A N-glycosyl-1,2,4-triazine that is 6-azauridine acetylated at positions 2', 3' and 5' on the sugar ring. It is a prodrug for 6-azauridine and is used for treatment of psoriasis.
World Health Organization (WHO)
Azaribine, an antineoplastic agent, was introduced in 1975 for the
treatment of severe, recalcitrant, disabling arthritis. Following reports of
thromboembolic and thrombotic reactions, the drug was withdrawn in the USA in
1976. The causal relationship between azaribine and these events has been
questioned and the drug remains available in the USA for investigational purposes.