SB 224289 HYDROCHLORIDE

SB-224289 Hydrochloride is a selective SR-1B antagonist; 5-HT1B antagonist.

SB 224289A is a 5-HT1B antagonist.

ChEBI: SB 224289 hydrochloride is a hydrochloride that is the monohydrochloride salt of SB 224289. Selective 5-HT1B receptor antagonist (pKi = 8.2). Displays >60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo. It has a role as a prodrug and a serotonergic antagonist. It contains a SB 224289(1+).

Room temperature