SB 243213 dihydrochloride (0.1-10 mg/kg; p.o.; 1 h pre-test) dose-dependently and significantly increases the amount of time rats spent in social interaction over 15 min under brightly lit conditions and in an unfamiliar test box[1].
SB 243213 dihydrochloride (0.3 mg/kg; p.o.; 1 h pre-test) significantly increases time spent in social interaction[1].
| Animal Model: | Male Sprague-Dawley experimentally naive rats (220-300 g)[1] |
| Dosage: | 0.1, 0.3, 1, 3, 10 mg/kg |
| Administration: | p.o.; 1 hour pre-test |
| Result: | Dose-dependently and significantly increased the amount of time rats spent in social interaction over 15 min under brightly lit conditions and in an unfamiliar test box.
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