1-ethyl-3-nitrobenzene

Product Name1-ethyl-3-nitrobenzene
CAS7369-50-8
MFC8H9NO2
MW151.16
EINECS230-923-6
MOL File7369-50-8.mol

Chemical Properties

Melting point	-37.9°C
Boiling point	242.55°C
Density	1.1345
refractive index	1.5359 (estimate)
storage temp.	Store at room temperature
Appearance	Light yellow to yellow Liquid

Usage And Synthesis

Uses

1-ethyl-3-nitrobenzene is used as an organic synthesis intermediate for the synthesis of m-nitroacetylbenzene.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 1321, 1987 DOI: 10.1016/S0040-4039(00)95359-0

Synthesis

586-39-0

7369-50-8

587-02-0

General method: 0.015 g of catalyst was dissolved with 2 mmol of 3-nitrostyrene in 10 mL of ethanol under standard reaction conditions in a hydrogen atmosphere. The reaction process was monitored in real time by thin layer chromatography (TLC). After complete conversion of the feedstock, the catalyst was removed by simple filtration, followed by evaporation of the solvent under reduced pressure to obtain purified 1-ethyl-3-nitrobenzene or 3-ethylaniline.

References

[1] Advanced Synthesis and Catalysis, 2012, vol. 354, # 4, p. 663 - 669
[2] Journal of Molecular Catalysis A: Chemical, 2012, vol. 365, p. 115 - 119
[3] ChemCatChem, 2015, vol. 7, # 4, p. 635 - 642
[4] Angewandte Chemie - International Edition, 2015, vol. 54, # 9, p. 2661 - 2664
[5] Angew. Chem., 2015, vol. 127, # 9, p. 2699 - 2702,3