white to light yellow crystalline powder
N-(Phenylseleno)phthalimide is a versatile selenamide reagent and has been used:
- to selectively derivatize thiols for mass spectrometric analysis
- to derivatize thiol peptides in protein digests
- in L-prolinamide or pyrrolidine trifluoromethanesulfonamide promoted α-selenenylation reactions of aldehydes and ketones
- for introducing PhSe into protected glycals, ketones, aldehydes, stannanes and exocyclic alkenes
N-(Phenylseleno)phthalimide can be prepared in 87% yield by the reaction of Benzeneselenenyl Chloride with potassium Phthalimide in hexane.
indefinitely stable when stored at -20 °C in the dark.
