莰菲醇-3-O-芸香糖苷
莰菲醇-3-O-芸香糖苷 性质
| 熔点 | 200°C (dec.) |
|---|---|
| 沸点 | 941.7±65.0 °C(Predicted) |
| 密度 | 1.76 |
| 储存条件 | Inert atmosphere,Store in freezer, under -20°C |
| 溶解度 | 可溶于氯仿（少许）、DMSO（少许）、甲醇（少许） |
| 形态 | 固体 |
| 酸度系数(pKa) | 6.20±0.40(Predicted) |
| 颜色 | 灰白色至黄色 |
| 生物来源 | plant (Clematis cultivar) |
| 稳定性 | 吸湿性 |
| 化妆品成分功效 | 抗氧化剂 皮肤调理 - 润肤剂 皮肤保护 |
| InChIKey | RTATXGUCZHCSNG-FVJKAJKWNA-N |
| SMILES | C1(O[C@H]2[C@H](O)[C@H]([C@H](O)[C@@H](CO[C@@H]3O[C@H]([C@H](O)[C@@H](O)[C@H]3O)C)O2)O)C(=O)C2=C(C=C(O)C=C2O)OC=1C1C=CC(O)=CC=1 |&1:2,3,5,6,8,11,13,14,16,18,r| |
莰菲醇-3-O-芸香糖苷 用途与合成方法
| Target | Value |
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p-JAK2
() | |
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p-STAT3
() | |
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caspase-3
() | |
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Bax
() | |
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Bcl-2
() |
For primarily cultured neurons suffered 2 h hypoxia followed by 24 h reoxygenation, nicotiflorin significantly attenuates cell death and reduces LDH release. Morphological observation also directly confirms its protective effect on neuron. After total 4 h hypoxia and 12 h reoxygenation, eNOS activity, mRNA and protein levels in the primarily cultured rat cerebral blood vessel endothelial cells treated with nicotiflorin (25-100 g/mL) 2 h after onset of hypoxia are significantly higher than eNOS activity, mRNA and protein levels in the pure H-R cells and also higher than eNOS activity, mRNA and protein levels in cells cultured under normoxic conditions.
At doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits. Nicotiflorin (2.5-10 mg/kg) administered after onset of ischemia markedly reduces brain infarct volume by 24.5-63.2% and neurological deficits.
药理药效:降血脂、善痴呆症状和记忆保护
莰菲醇-3-O-芸香糖苷 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-09-15 | HY-N1475R | 莰菲醇-3-O-芸香糖苷 | 17650-84-9 | 5 mg | 2160 |
| 2026-09-15 | HY-N1475 | 莰菲醇-3-O-芸香糖苷 | 17650-84-9 | 1 mg | 450 |
