Nickel chloride, dimethoxyethane adduct

NiCl2 (100 g, 771.6 mmol) was dissolved in a mixture of 300 mL methanol and 50 mL trimethyl orthoformate and refluxed with stirring overnight. After the reaction was complete, unreacted NiCl2 was removed by filtration, and 80% of the solution was removed under reduced pressure to obtain a green gel. This gel was dissolved in a minimal amount of methanol, and 300 mL DME was added. The solution was refluxed with stirring overnight. A yellow powder precipitate of NICKEL CHLORIDE, DIMETHOXYETHANE ADDUCT was separated by tube filtration. The powder was washed with pentane and dried under a nitrogen stream.

• As a catalyst for the borylation of racemic benzylic chloride to synthesize enantioenriched benzylic boronic esters.
• As a promoter for the trifluoromethylation of alkyl iodides to synthesize broad range of alkyl-CF₃ compounds.
• For the synthesis of nickel bis(benzimidazol-2-ylidene) pincer complexes which can be used for electrocatalytic reduction of CO₂ to CO.
• As a Lewis acid catalyst for C-acylation β-ketoesters through photoactivation by visible light.