氢化可的松环戊丙酸酯
氢化可的松环戊丙酸酯 性质
沸点 | 645.0±55.0 °C(Predicted) |
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密度 | 1.22±0.1 g/cm3(Predicted) |
储存条件 | Store at -20°C |
溶解度 | 二甲基亚砜:125 mg/mL(256.86 mM) |
形态 | 固体 |
酸度系数(pKa) | 12.33±0.70(Predicted) |
颜色 | 白色至米白色 |
氢化可的松环戊丙酸酯 用途与合成方法
Hydrocortisone (50 nM) shows a dose-dependent down-regulation of GR transcript in hCMEC/D3 cells. Hydrocortisone supplementation of the serum-reduced cell differentiation medium leads to a significant increase in TER across the hCMEC/D3 monolayer. Hydrocortisone-treated Dendritic cells (DCs) show a decreased expression of MHC II molecules, the costimulatory molecule CD86, and the DC-specific marker CD83, as well as a strongly reduced IL-12 secretion. Hydrocortisone-treated DCs inhibit production of IFN-γ but induce an increased release of IL-4 and no change in IL-5. Hydrocortisone reduces postischemic oxidative stress, perfusion pressure, and transudate formation. Hydrocortisone inhibits postischemic shedding of syndecan-1, heparan sulfate, and hyaluronan as is release of histamine from resident mast cells.
氢化可的松环戊丙酸酯 价格(试剂级)
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024-11-08 | HY-U00089 | 氢化可的松环戊丙酸酯 | 508-99-6 | 1mg | 800 |
2024-11-08 | HY-U00089 | 氢化可的松环戊丙酸酯 | 508-99-6 | 5mg | 1800 |