Yellow to light yellow crystal
4,6-Diaminopyrimidine is a compound used for the preparations of pharmaceutical goods. It was shown that organotin polyamines derived from reaction with 4,6-diaminopyrimidines displayed good inhibition of two pancreatic cancer cell lines.
General procedure for the synthesis of 4,6-diaminopyrimidine from the compound (CAS:40070-06-2): 250 mL of 11.5 mol/L hydrochloric acid solution was added to the 4,6-diamino-2-sulfinic acid pyrimidine filter cake obtained in step 2, and the mixture was cooled to -5 °C and stirred continuously for 0.5 h. The mixture was then purified to -5 °C and stirred continuously for 0.5 h. The mixture was purified to -5 °C and stirred continuously for 0.5 h. The mixture was purified to -5 °C and stirred continuously for 0.5 h. The yield of this step was 100%.
[1] Patent: CN103709164, 2016, B. Location in patent: Paragraph 0034; 0090; 0105; 0108
[2] Journal of the Chemical Society, 1946, p. 4106,4109
