White, crystals or powder, odorless;
tasteless. Slightly soluble in water and alcohol; very
slightly soluble in chloroform, ether; pH of 1% solution is between 4.5 and 6.5.
Buphenine
hydrochloride,Troponwerke
Medicine (treatment of heart disease).
ChEBI: Nylidrin hydrochloride is an alkylbenzene.
The p-benzoxy-α-bromopropiophenone and 1-phenyl-3-amino-butane were
heating for an hour on the water bath in the absence of solvents. A solid
crystalline cake was obtained. After being extracted with boiling acetic acid,
the hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-1
was obtained.
The hydrobromide of 1-(p-hydroxyphenyl)-2-(β-phenylbutylamino)propanone-
1 was suspended in very pure methanol and shaken with a 10% palladium
hydroxide barium sulfate catalyst in contact with, hydrogen. After rather more
than 2 mols of hydrogen had been taken-up the hydrogenation stopped. The
1-(p-hydroxyphenyl)-2-(3-phenylbutylamino)propanol-1, was filtered, washed
with methanol and evaporated, melting point 110-111°C.