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2-Amino-4-phenylbutane

Product Name2-Amino-4-phenylbutane
CAS22374-89-6
MFC10H15N
MW149.24
EINECS244-942-2
MOL File22374-89-6.mol

Chemical Properties

Melting point	-50°C
Boiling point	228-232 °C (lit.)
Density	0.922 g/mL at 25 °C (lit.)
vapor pressure	10.146Pa at 25℃
refractive index	n20/D 1.514(lit.)
Flash point	208 °F
storage temp.	−20°C
solubility	soluble in Chloroform, Ethyl Acetate
form	liquid
pka	pKa 10.0 (Uncertain)
Specific Gravity	0.922
color	Clear
PH	11.6 (10g/l, H2O, 20℃)
Water Solubility	8.5 g/L (20 ºC)
Sensitive	Air Sensitive
BRN	2413110
InChI	1S/C10H15N/c1-9(11)7-8-10-5-3-2-4-6-10/h2-6,9H,7-8,11H2,1H3
InChIKey	WECUIGDEWBNQJJ-UHFFFAOYSA-N
SMILES	CC(N)CCc1ccccc1
LogP	2.12
CAS DataBase Reference	22374-89-6(CAS DataBase Reference)
NIST Chemistry Reference	Benzenepropanamine, «alpha»-methyl-(22374-89-6)

Safety Information

Hazard Codes	C,Xi,T,F
Risk Statements	34-22-39/23/24/25-23/24/25-11
Safety Statements	26-36/37/39-45-28A-36/37
RIDADR	UN 2735 8/PG 3
WGK Germany	2
RTECS	UI3920000
Hazard Note	Irritant
HazardClass	8
PackingGroup	III
HS Code	29214980
Storage Class	6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
Hazard Classifications	Acute Tox. 3 Dermal Acute Tox. 3 Oral Aquatic Chronic 3 Eye Dam. 1 Skin Corr. 1B
Toxicity	LD orl-rat: >600 mg/kg AEPPAE 195,647,1940

MSDS

Provider	Language
2-Amino-4-phenylbutane	English

Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

2-Amino-4-phenylbutane is used in the synthesis of N-substituted derivatives of (1-methyl-3- phenylpropyl)amine.

Biological Functions

Amphetamine is an indirectly acting adrenomimetic amine that depends for its action on the release of norepinephrine from noradrenergic nerves. Its pharmacological effects are similar to those of ephedrine; however, its CNS stimulant activity is somewhat greater. Both systolic and diastolic blood pressures are increased by oral dosing with amphetamine. The heart rate is frequently slowed reflexively. Cardiac output may remain unchanged in the low- and moderate-dose range. The therapeutic uses of amphetamine are based on its ability to stimulate the CNS. The D-isomer (dextroamphetamine) is three to four times as potent as the L-isomer in producing CNS effects. It has been used in the treatment of obesity because of its anorexic effect, although tolerance to this effect develops rapidly. It prevents or overcomes fatigue and has been used as a CNS stimulant. Amphetamine is no longer recommended for these uses because of its potential for abuse. Amphetamine is useful in certain cases of narcolepsy or minimal brain dysfunction.

Flammability and Explosibility

Not classified

Safety Profile

A poison by intraperitoneal and parenteral route. Moderately toxic by ingestion.When heated to decomposition it emits toxic vapors of NOx.

Synthesis

Amphetamine is prepared by treating phenylacetone with formic acid and ammonia under the Leuckart-Wallach conditions .

2-Amino-4-phenylbutane

Chemical Properties

Safety Information

MSDS

Usage And Synthesis

Preparation Products And Raw materials

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