L-胱硫醚
L-胱硫醚 性质
| 熔点 | 312 |
|---|---|
| 比旋光度 | D20 +23.7° (1N HCl) |
| 密度 | 1.430±0.06 g/cm3 (20 ºC 760 Torr) |
| 储存条件 | -20°C |
| 溶解度 | 酸水溶液（微溶） |
| 形态 | 固体 |
| 沸点 | 481.0±45.0 °C(Predicted) |
| 酸度系数(pKa) | 2.08±0.10(Predicted) |
| 颜色 | 白色至类白色 |
| 旋光性 (optical activity) | +26.425 (1 mol dm-3 HCl) |
| Merck | 13,2807 |
| BRN | 2505200 |
L-胱硫醚 用途与合成方法
|
Human Endogenous Metabolite
|
Homocysteine obviously induces the apoptosis of HUVECs, and this effect is significantly attenuated by the pretreatment with L-cystathionine. Furthermore, L-cystathionine decreases the production of mitochondrial superoxide anion and the expression of Bax and restrained its translocation to mitochondria, increases mitochondrial membrane potential, inhibits mitochondrial permeability transition pore (MPTP) opening, suppresses the leakage of cytochrome c from mitochondria into the cytoplasm, and downregulated activities of caspase-9 and caspase-3.
L-Cystathionine is an important metabolic intermediate in the L-cysteine transsulfuration pathway from L-methionine via L-homocysteine in mammalian tissues.
由邻琥珀酰高丝氨酸与半胱氨酸作用生成。胱硫醚被胱硫醚β
-
裂解酶作用脱去丙酮酸和
NH3
后生成高半胱氨酸。
L-胱硫醚 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-11-08 | HY-W009749 | 1 mg | 450 | ||
| 2024-11-08 | HY-W009749 | L-胱硫醚 | 56-88-2 | 5 mg | 1180 |
