White crystalline solid. Some formulations
are a dark brown liquid.
Plant growth regulator and herbicide used in lawns, turf, grassland, industrial areas
and areas where grass cutting is difficult such as embankments. Also used to enhance
sucrose content in sugarcane.
Mefluidide is a plant growth regulator that suppresses annual bluegrass seedheads on creeping bentgrass greens. An antiparasitic agent.
Plant growth regulator; herbicide.
The industrial synthesis of mefluidide begins with the derivatization of 2,4-dimethylaniline, which is acylated using acetic anhydride or acetyl chloride to form the acetanilide backbone. This intermediate then undergoes sulfonamidation with trifluoromethanesulfonyl chloride (triflic anhydride) under basic conditions to introduce the trifluoromethanesulfonamide group at the para position. The reaction is typically carried out in an organic solvent such as dichloromethane or acetonitrile, with a base like triethylamine to neutralise the by-product acid.
ChEBI: Mefluidide is a sulfonamide.
Herbicide; plant growth regulator: Not approved for use in EU countries
. Mefluidide
is used to control ornamental and non-ornamental woody
plants, ground cover, hedges, trees, turfgrass and broadleaf
weeds. Both the diethanolamine and potassium salts are
actively used in the U.S.
EMmHgK®; MBR 12325®; MBR
12325®; METHAFLUORIDAMID®; S 15733®; VEL
3973®; VISTAR® Herbicide
Growth inhibition, absorbed by foliage. Gibberellin biosynthesis inhibitor
Mefluidide is an anilide herbicide and
plant growth regulator used to control ornamental and nonornamental woody plants, ground cover, hedges, trees, turfgrass, and broadleaf weeds. Both the diethanolamine and
potassium salts are actively used in the United States Not
refistered for use in the EU.
Soil. Rapidly degrades in soil forming 5-amino-2,4-dimethyltrifluoromethane sulfone
anilide as the major metabolite (half-life <1 week) (Hartley and Kidd, 1987).
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required
May react with strong oxidizers such as
chlorates, peroxides, nitrates, etc
Dissolve or mix the material
with a combustible solvent and burn in a chemical
incinerator equipped with an afterburner and scrubber.
All federal, state, and local environmental regulations
must be observed.
Herbicide; Plant Growth Regulator
