链球菌溶素O
链球菌溶素O 性质
| 储存条件 | 2-8°C |
|---|---|
| 溶解度 | 水中的溶解度为1mg/mL |
| 形态 | 冻干粉 |
| 颜色 | 白色 |
| 水溶解性 | H2O: soluble 1mg/mL |
| Specific Activity | 25,000-50,000U/vial |
链球菌溶素O 用途与合成方法
Streptolysin O is a labile toxin, and, with time, activity is irreversibly lost. The rate of activity loss is slowed by incubation with 0.1 M 2-mercaptoethanol or 0.01 M ethylenediaminetetraacetic acid (EDTA).
Streptolysin O, belongs to the group of thiol-activated toxins, is a secreted virulence factor of GAS that induces apoptosis in neutrophils and macrophages at later time points (~4 h). Streptolysin O induces eukaryotic cell lysis in a cholesterol-dependent manner, is highly upregulated in the GAS M1T1 clone during bloodstream dissemination. Streptolysin O is known to promote Group A Streptococcus (GAS) resistance to phagocytic clearance by neutrophils, a critical first element of host defense against invasive bacterial infection.
安全信息
| 危险品运输编号 | UN 2811PIH 6.1 / PGI |
|---|---|
| WGK Germany | 3 |
| 存储类别 | 6.1A - 可燃，急性毒性物质（类别1和类别2） 剧毒的危险物质 |
| 危险性类别 | 急性毒性 类别2 经皮 急性毒性 类别2 吸入 急性毒性 类别2 经口 危害水生环境-长期危害 类别2 严重眼损伤 类别1 经皮刺激 类别2 |
链球菌溶素O 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026-06-05 | HY-135416A | 链球菌溶素O | 98072-47-0 | 100 KU | 8075 |
| 2026-06-05 | HY-135416 | 链球菌溶素O | 98072-47-0 | 25KU | 5580 |
