4-(2H-Tetrazol-5-yl)-phenylamine

16687-60-8

46047-18-1

General procedure for the synthesis of 5-(4-aminophenyl)-2H-tetrazole from 5-(4-nitrophenyl)-1H-tetrazole: 5-(4-nitrophenyl)-1H-tetrazole (5.3 g, 27.7 mmol), anhydrous ethanol (50 mL), ethyl acetate (50 mL), and 10% palladium-carbon-caprolactone catalyst (500 mg) were added to an autoclave reactor, and reacted under hydrogen atmosphere ( 30 psi) for 16 hours. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filter cake was washed with ethyl acetate. The filtrate was concentrated under reduced pressure to afford 4-(1H-tetrazol-5-yl)aniline as a light orange solid (4.5 g, 100% yield).