2-(2-Benzothiazolyl)acetic acid ethyl ester

105-56-6

137-07-5

29182-42-1

To a mixture of 2-aminothiophenol (5 g, 39.9 mmol) was added ethyl cyanoacetate (4.25 ml, 39.9 mmol). The reaction mixture was heated to 120°C under stirring and maintained at this temperature for 3 hours. Upon completion of the reaction, the volatile components were removed by concentration under reduced pressure to give 8 g of ethyl 2-(benzo[d]thiazol-2-yl)acetate, the product being a brown oil in 90% yield.