antineoplastic; inhibitor DNA methylation
DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. It is also used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.
ChEBI: A non-proteinogenic alpha-amino acid that is methionine in which the S-methyl group is replaced by an S-ethyl group.
White crystalline flakes.
Slightly soluble in water.
A synthetic thio-substituted amino acid.
ACUTE/CHRONIC HAZARDS: When heated to decomposition DL-ETHIONINE emits toxic fumes of NOx and SOx.
Flash point data for DL-ETHIONINE are not available; however, DL-ETHIONINE is probably combustible.
DL-Ethionine is a racemic mixture of the anti-methylation agent L-Ethionine and its enantiomer D-Ethionine. DL-Ethionine is used as a dietary supplement to accelerate cholangiocarcinogenesis in vivo. DL-Ethionine is used to induce oxidative stress in liver to study the levels and activities of anti-oxidative enzymes and compounds such as glutathione.
Mddly toxic by
ingestion and intraperitoneal routes.
Suspected carcinogen with experimental
carcinogenic and tumorigenic data. An
experimental teratogen. Experimental reproductive effects. Mutation data
reported. When heated to decomposition it
emits toxic fumes of SOx and NOx.
