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Thymidine

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Thymidine Basic information
Thymidine Chemical Properties
  • Melting point:186-188 °C(lit.)
  • alpha 18.6 º (c=3, H2O)
  • Boiling point:385.05°C (rough estimate)
  • Density 1.3129 (rough estimate)
  • refractive index 33 ° (C=1, 1mol/L NaOH)
  • storage temp. 2-8°C
  • pkapK1:9.79;pK2:12.85 (25°C)
  • form Crystalline Powder
  • color White to almost white
  • optical activity[α]20/D +19±1°, c = 1% in H2O
  • Water Solubility SOLUBLE
  • Merck 14,9397
  • BRN 89285
  • Stability:Stable. Incompatible with strong oxidizing agents.
  • InChIKeyIQFYYKKMVGJFEH-XLPZGREQSA-N
  • CAS DataBase Reference50-89-5(CAS DataBase Reference)
  • NIST Chemistry ReferenceThymidine(50-89-5)
  • EPA Substance Registry SystemThymidine (50-89-5)
Safety Information
MSDS
Thymidine Usage And Synthesis
  • Chemical PropertiesWhite crystalline powder
  • UsesConstituent of deoxyribonucleic acid
  • UsesUsed for e.g. syntheses of zidovudine. Attributes For further information please contact us Contact
  • DefinitionThe nucleoside (deoxyriboside) of thymine. Occurs in DNA.
  • DefinitionThe NUCLEOSIDE formed when thymine is linked to D-ribose by a β-glycosidic bond.
  • Definitionthymidine: A nucleoside consistingof one thymine molecule linked to ad-doxyribose sugar molecule.
  • Safety ProfileModerately toxic by intraperitoneal route. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Purification MethodsCrystallise -thymidine from ethyl acetate, MeOH/Et2O (m 188o) or H2O (as 2H2O m 189o). It is soluble in water and hot organic solvents. The picrate has m 230o (from EtOH).
Thymidine Preparation Products And Raw materials
Thymidine(50-89-5)Related Product Information
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