ChemicalBook Product Catalog API Antineoplastic agents Other antineoplastic Drugs Trabedersen

Trabedersen

Chemical Properties

form	Solid
color	White to off-white
Sequence	DNA, d(P-thio)(C-G-G-C-A-T-G-T-C-T-A-T-T-T-T-G-T-A)

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Animal Model:	Eight-week-old male athymic nude mice (BALBCnu nu) bearing human pancreatic cancer cells^[2].
Dosage:	Initial loading dose of 50 mg/kg bodyweight followed by 16 mg/kg three times a week.
Administration:	Intraperitoneal (i.p.) injection; three times a week; for 27 days
Result:	Significantly reduced tumor growth, lymph node metastasis and angiogenesis.