4,4'-DIFLUOROBENZIL

pale yellow powder

4,4′-Difluorobenzil is suitable for use in the preparation of 2,3-bis(4-fluorophenyl)thieno[3,4-b]pyrazine. It may be used in the synthesis of following:

• poly(ether-α-diketone)s, via nucleophilic substitution reaction with bisphenol A
• 4,4′-difluoro-2,3-diphenylpyrazine (DPPF) and 4,4′-difluoro-5-methyl 2,3-diphenylpyrazine (MDPPF), via direct condensation with ethylenediamine and 1,2-diaminopropane, respectively
• 2,3-bis(4-fluorophenyl)quinoxaline, via direct condensation with 1,2-phenylenediamine

Tetrahedron Letters, 35, p. 2959, 1994 DOI: 10.1016/S0040-4039(00)76671-8

4,4′-Difluorobenzil is a benzil derivative. Its reaction with benzylurea and phenethylurea has been investigated. It is reported to undergo condensation with Fe₂(SH)₂(CO)₆ to afford the adduct Fe₂[S₂C₂(OH)₂(C₆H₄-4-F)₂](CO)₆.