(+/-) 14,15-DIHETE

(±)14(15)-DiHETE is an oxylipin and a metabolite of the ω-3 fatty acid eicosapentaenoic acid (EPA; Item Nos. 90110 | 90110.1 | 21908).1,2 It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Item No. 10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase.WARNING This product is not for human or veterinary use.

[1] HULDA S. JÓNASDÓTTIR. An Advanced LC–MS/MS Platform for the Analysis of Specialized Pro-Resolving Lipid Mediators[J]. Chromatographia, 2014, 78 5-6: 391-401. DOI: 10.1007/s10337-014-2779-5
[2] GREGORY C SHEARER. Detection of omega-3 oxylipins in human plasma and response to treatment with omega-3 acid ethyl esters.[J]. Journal of Lipid Research, 2010: 2074-2081. DOI: 10.1194/m900193-jlr200