(14(15)-DiHET-d11

(±)14,15-DiHET-d11 is intended for use as an internal standard for the quantification of 14(15)-DiHET by GC- or LC-MS. 14(R),15(R)-DiHET and 14(S),15(S)-DiHET are vicinal diols formed via enzymatic hydration of 14(15)-EET by cytosolic or soluble epoxide hydrolases.1,2 14(R),15(R)-DiHET is produced at a greater proportion than 14(S),15(S)-DiHET by cytosolic epoxide hydrolase.1WARNING This product is not for human or veterinary use.

[1] D C ZELDIN. Regio- and enantiofacial selectivity of epoxyeicosatrienoic acid hydration by cytosolic epoxide hydrolase.[J]. The Journal of Biological Chemistry, 1993, 268 9: 6402-6407.
[2] GUODONG ZHANG  Bruce D H  Sean Kodani. Stabilized epoxygenated fatty acids regulate inflammation, pain, angiogenesis and cancer[J]. Progress in lipid research, 2014, 53: Pages 108-123. DOI: 10.1016/j.plipres.2013.11.003