N,N′-Diisoprophyl phosphordiamide fluoride

Chemical Properties

Melting point	65°
Boiling point	125.5°C
Density	1.2 g/cm3(Temp: 25 °C)
pka	-2.71±0.70(Predicted)
form	solid
Water Solubility	74.07g/L(temperature not stated)
EPA Substance Registry System	Mipafox (371-86-8)

Hazard Codes	T+
Risk Statements	39/26/27/28
Safety Statements	13-45
RIDADR	2783
HazardClass	6.1(b)
PackingGroup	III
Hazardous Substances Data	371-86-8(Hazardous Substances Data)
Toxicity	Formerly used as a systemic insecticide. Its use was discontinued because of severe delayed neuropathy hazard in humans. The oral LD50/LC50 in rabbits is 100 mg/kg. Toxic action is as a neurotoxicant with both acute and delayed actions, acting as a cholinesterase inhibitor (acute toxicity) and as a neurotoxic esterase inhibitor (possibly linked to delayed toxicity). Symptoms in humans are typical anticholinesterase symptoms. Therapy is supportive as well as atropine sulfate and 2-PAM.