(-)-7-Methoxyrosmanol ((-)-7-O-Methoxyrosmanol) is a phenolic diterpene with antioxidant activity. (-)-7-Methoxyrosmanol is produced from carnosic acid by oxidation and cyclization, can induce cell cycle arrest and apoptosis in neuroblastoma cells[1][2][3].
[1] Tabata K, et al. Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells. Anticancer Res. 2012 Nov;32(11):4781-9. PMID:23155243
[2] Jiang Z Y, et al. Perovskatone A: a novel C23 terpenoid from Perovskia atriplicifolia[J]. Tetrahedron letters, 2013, 54(29): 3886-3888.
[3] Richheimer S L, et al. Antioxidant activity of lipid-soluble phenolic diterpenes from rosemary[J]. Journal of the American Oil Chemists’ Society, 1996, 73(4): 507-514.
